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Related Experiment Videos

Pain perception with pH buffered peribulbar anaesthesia: a pilot study.

M C Minasian1, A C Ionides, R Fernando

  • 1Department of Ophthalmology, Royal Free Hospital, London NW3 2QG.

The British Journal of Ophthalmology
|September 1, 2000
PubMed
Summary

Alkalinizing local anaesthetic solutions did not reduce pain during peribulbar injections. Patient pain perception was similar between buffered and unbuffered solutions, highlighting the importance of individual pain thresholds.

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Area of Science:

  • Ophthalmology
  • Anesthesiology

Background:

  • Peribulbar anesthesia is commonly used for ophthalmic surgery.
  • Patient-reported pain during local anesthesia injection is a significant concern.

Purpose of the Study:

  • To investigate the effect of alkalinized local anesthetic solutions on pain perception during peribulbar injections.
  • To determine if adjusting the pH of anesthetic solutions can improve patient comfort.

Main Methods:

  • A prospective, randomized, double-blind pilot study.
  • 60 patients received peribulbar blocks with either standard acidic or pH-7.44 alkalinized local anesthetics.
  • Pain was assessed using a visual analog scale for dilating drops and injections.

Main Results:

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  • Mean pain scores were similar between the acidic (4.84) and alkalinized (4.97) solution groups.
  • No significant difference in pain was observed between the two groups.
  • A strong association was found between pain from dilating drops and injection pain (p<0.0001).

    • Conclusions:

    • Buffering local anesthetics to a pH of 7.44 does not reduce pain associated with peribulbar injections.
    • Individual pain threshold, particularly from preoperative dilating drops, is a significant factor influencing overall pain perception.
    • Further research may be needed to explore other methods for pain reduction in peribulbar anesthesia.