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Milia en plaque: a new site
Q A Alsaleh1, A Nanda, A Sharaf
1As'ad Al-Hamad Dermatology Center, Al-Sabah Hospital, Kuwait.
International Journal of Dermatology
|September 6, 2000
Summary
This case study highlights a rare presentation of milia on the face. Minocycline treatment effectively reduced facial milia and associated erythema in a field worker.
Area of Science:
- Dermatology
- Pathology
Background:
- Facial milia, characterized by keratin-filled cysts, can present as asymptomatic papules.
- Differential diagnosis for facial papules includes various inflammatory and non-inflammatory conditions.
Observation:
- A 35-year-old Kuwaiti male field worker presented with an asymptomatic erythematous plaque on his nasal bridge, extending to the malar area.
- The plaque was studded with yellowish papules and accompanied by discrete milia on the cheek.
- Histopathology confirmed multiple keratin-filled cysts with a dense lymphocytic infiltrate, consistent with milia.
Findings:
- Topical tretinoin 0.05% twice daily for one month showed no improvement.
- Oral minocycline 100 mg daily resulted in a significant decrease in erythema and milia count after one month.
Implications:
- This case suggests oral minocycline as a potential therapeutic option for recalcitrant facial milia.
- Further research may explore the anti-inflammatory mechanisms of minocycline in milia treatment.
