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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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AI Dermatology's Unfulfilled Promise: Why Early Melanoma Detection Remains Unverified

Tim J Zeuner1,2, Titus J Brinker1

  • 1Division of Digital Prevention, Diagnostics and Therapy Guidance, German Cancer Research Center (DKFZ), Heidelberg, Germany.

International Journal of Dermatology
|September 29, 2026
PubMed

Keywords:
Breslow thicknessartificial intelligencedermoscopydiagnostic uncertaintyearly detectionexplainable AIhistopathologylongitudinal imagingmachine learningmelanoma

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Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...