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The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human
S Hellebrand1, H C Schaller, T Wittenberger
1Zentrum für Molekulare Neurobiologie, Institut für Entwicklungsneurobiologie, Martinistrasse 52, D-20246, Hamburg, Germany. hellbrnd@zmnh.uni-hamburg.de
Biochimica Et Biophysica Acta
|September 9, 2000
Abstract:
A new G-protein coupled receptor, GPR85, was identified in man and mouse, which is completely conserved at the amino acid level. Transcripts of gpr85 were found in several human brain regions and, at lower levels, in spleen and placenta, whereas in mouse, gpr85 is confined to the brain. The hgpr85 gene was localized to human chromosome 7q31 by the polymerase chain reaction utilizing a radiation hybrid panel.