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Osteonecrosis following renal transplantation
Summary
Subarticular osteonecrosis is increasingly seen after renal transplantation and corticosteroid use. This study details six cases, highlighting common sites and outlining treatment approaches for this complication.
Area of Science:
- Nephrology
- Orthopedic Surgery
- Transplantation Medicine
Background:
- Subarticular osteonecrosis is a growing concern following renal transplantation.
- Immunosuppressive corticosteroid therapy is a significant contributing factor.
Purpose of the Study:
- To report on the incidence and characteristics of subarticular osteonecrosis in renal transplant recipients.
- To describe radiological and pathological findings.
- To consider pathogenesis and outline treatment strategies.
Main Methods:
- Retrospective review of six cases of subarticular osteonecrosis among 170 renal transplant patients.
- Analysis of radiological and morbid anatomical features.
- Review of existing literature on pathogenesis and treatment.
Main Results:
- Six cases of subarticular osteonecrosis were identified in 170 renal transplant patients.
- Commonly affected sites include the femoral head, femoral condyles, humeral head, talus, and capitulum.
- Radiological and pathological features of the complication were documented.
Conclusions:
- Subarticular osteonecrosis is a notable complication in renal transplant recipients, particularly with corticosteroid immunosuppression.
- Understanding the affected sites and pathogenesis is crucial for management.
- An approach to treatment is proposed based on observed cases.