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Antimicrobial resistance in human populations: challenges and opportunities

S Allcock1,2, E H Young1,2, M Holmes3

  • 1Department of Medicine, University of Cambridge, Cambridge, UK.

Global Health, Epidemiology and Genomics
|December 26, 2017
PubMed

Insights

Antimicrobial resistance (AMR) is a growing global threat. Population-based studies are crucial for understanding AMR

Area of Science:

  • Public Health
  • Microbiology
  • Epidemiology

Background:

  • Antimicrobial resistance (AMR) poses a significant global health challenge.
  • The emergence and spread of AMR are influenced by antimicrobial exposure in clinical and veterinary settings.
  • Current understanding of AMR burden, distribution, and determinants at the population level is limited.

Purpose of the Study:

  • To emphasize the critical need for population-based approaches in studying AMR.
  • To assess the association between antimicrobial use and AMR in human and animal populations.
  • To inform strategies for AMR prevention, detection, management, and sustainable antimicrobial use.

Main Methods:

  • Population-based studies.
  • Epidemiological assessments.
  • Analysis of antimicrobial use patterns and AMR data.

Main Results:

  • Population-based approaches are essential for understanding AMR.
  • These methods can elucidate the link between antimicrobial consumption and resistance.
  • Improved understanding is vital for effective AMR control strategies.

Conclusions:

  • Population-based studies are indispensable for addressing the global AMR crisis.
  • Integrating antimicrobial use data with resistance surveillance is key.
  • Such integrated approaches will support sustainable antimicrobial stewardship in healthcare and beyond.
Keywords:
Animalantimicrobialhumanmultidrug-resistantresistance

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