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Related Experiment Videos

How should we assess diastolic function in hypertension?

L Bojö1, B Wandt, S Haaga

  • 1Department of Clinical Physiology, Central Hospital, Karlstad, Sweden.

Scandinavian Cardiovascular Journal : SCJ
|September 13, 2000
PubMed
Summary
This summary is machine-generated.

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Maximal longitudinal LV relaxation velocity (RVm) is the most effective index for assessing diastolic function in hypertensive patients with normal systolic function, showing a clearer distinction compared to E/A ratio and atrial to total mitral annulus motion (AC).

Area of Science:

  • Cardiology
  • Cardiovascular Physiology
  • Echocardiography

Background:

  • Hypertension is a common condition that can lead to diastolic dysfunction.
  • Assessing diastolic function is crucial for managing cardiovascular risk.
  • Existing indices for diastolic function assessment show limitations in differentiating hypertensive patients.

Purpose of the Study:

  • To compare the effectiveness of three echocardiographic indices of diastolic left ventricular (LV) function.
  • To identify the most suitable index for evaluating diastolic LV function in hypertensive patients with preserved systolic function.

Main Methods:

  • Echocardiographic assessment of diastolic LV function using E/A ratio, atrial to total mitral annulus motion (AC), and maximal longitudinal LV relaxation velocity (RVm).

Related Experiment Videos

  • Study included 19 hypertensive patients with normal systolic function and 20 healthy controls.
  • Pulsed Doppler and M-mode recordings from apical views were utilized.

    • Main Results:

    • All three indices (E/A ratio, AC, RVm) indicated impaired diastolic function in hypertensive patients compared to controls.
    • E/A ratio and AC showed significant overlap between hypertensive patients and controls.
    • RVm demonstrated a highly significant difference between groups with minimal overlap, suggesting superior discriminatory power.

    Conclusions:

    • Maximal longitudinal LV relaxation velocity (RVm) appears to be the most appropriate index for assessing diastolic function in hypertensive patients with normal systolic function.
    • RVm offers better differentiation of diastolic dysfunction in this patient population compared to E/A ratio and AC.