Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Paraneoplastic rheumatic syndromes.

¹Division of Rheumatology, Sunnybrook Health Science Centre, University of Toronto, Toronto, Ontario, Canada.

Bailliere'S Best Practice & Research. Clinical Rheumatology

|September 14, 2000

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Acute calcium pyrophosphate dihydrate crystal-induced tenosynovitis.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2008

Same author

Current therapy of acute microcrystalline arthritis and the role of corticosteroids.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2008

Same author

Recent advances in the management of adult myositis.

Expert opinion on investigational drugs·2002

Same author

Cholesterol crystals in gouty bursitis.

The Journal of rheumatology·2001

Same author

Difficult gout and new approaches for control of hyperuricemia in the allopurinol-allergic patient.

Current rheumatology reports·2001

Same author

Efficacy and safety of desensitization to allopurinol following cutaneous reactions.

Arthritis and rheumatism·2001

Same journal

Preface

Bailliere's best practice & research. Clinical rheumatology·2000

Same journal

Index

Bailliere's best practice & research. Clinical rheumatology·2000

Same journal

How do we manage chronic pain?

Bailliere's best practice & research. Clinical rheumatology·2000

Same journal

The biopsychosocial model--a tool for rheumatologists.

Bailliere's best practice & research. Clinical rheumatology·2000

Same journal

The psychology of rheumatic diseases.

Bailliere's best practice & research. Clinical rheumatology·2000

Same journal

Physical therapy and rehabilitation in the management of rheumatic disorders.

Bailliere's best practice & research. Clinical rheumatology·2000

See all related articles

Cancer can trigger various rheumatological syndromes, often mimicking other conditions. Recognizing these paraneoplastic rheumatic disorders is crucial for early cancer diagnosis and treatment.

Area of Science:

Rheumatology
Oncology
Internal Medicine

Background:

Malignant neoplasms are linked to diverse paraneoplastic rheumatological syndromes.
Commonly observed syndromes include hypertrophic osteoarthropathy, carcinoma polyarthritis, dermatomyositis/polymyositis, and paraneoplastic vasculitis.
Less frequent associations involve fasciitis, panniculitis, erythema nodosum, Raynaud's syndrome, digital gangrene, erythromelalgia, and lupus-like syndromes.

Purpose of the Study:

To highlight the association between rheumatological syndromes and underlying malignancies.
To emphasize the importance of recognizing non-metastatic symptoms as potential indicators of occult cancer.
To guide early diagnosis and management of paraneoplastic rheumatic disorders.

Main Methods:

Related Experiment Videos

Review of literature on paraneoplastic rheumatological syndromes associated with malignant neoplasms.

Clinical observation of musculoskeletal manifestations preceding, coinciding with, or following cancer diagnosis.

Identification of key rheumatic symptoms suggestive of underlying cancer.

Main Results:

Musculoskeletal symptoms can precede, coincide with, or follow cancer diagnosis, and may indicate recurrence.
The course of rheumatic disorders often parallels the primary tumor's progression.
Successful treatment of the underlying malignancy frequently leads to regression of the rheumatic syndrome.

Conclusions:

Awareness of paraneoplastic rheumatological syndromes is vital for detecting hidden cancers.
Specific rheumatic manifestations like rapid inflammatory arthritis, bone pain in older adults, vasculitis, fasciitis, unresponsive Raynaud's syndrome, digital gangrene, or Lambert-Eaton myasthenic syndrome warrant investigation for malignancy.
Management involves treating the primary cancer and providing symptomatic relief for rheumatic symptoms.