Related Experiment Videos
Identification of the human Y-chromosomal microsatellite locus DYS19 from degraded DNA
1Institut für Rechtsmedizin, Otto-von-Guericke-Universität, Magdeburg, Germany.
The American Journal of Forensic Medicine and Pathology
|September 16, 2000
Abstract:
STR DYS19 seems to be one of the most useful markers for population genetic, evolutionary, and forensic applications. However, the authors have noticed that the amplification of the DYS19 polymorphism fails when highly degraded DNA is used as a template. The authors designed a new pair of primers that reduce the DYS19 fragment sizes compared with those of the known protocol. Using these primers, an improved success rate can be achieved, particularly when putrefied samples are under investigation.