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A new route to spirooxindoles
S T Hilton1, T C Ho, G Pljevaljcic
1School of Chemical and Pharmaceutical Sciences, Kingston University, Kingston-upon-Thames, Surrey, UK.
Organic Letters
|September 16, 2000
Abstract:
[reaction: see text]Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.