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[Iodine antiseptics are not harmless].

J Arena Ansotegui1, J I Emparanza Knörr

  • 1Unidad de Metabolopatías, Servicio de Pediatría, Hospital Aránzazu, San Sebastián. jarena@chdo.osakidetza.net

Anales Espanoles De Pediatria
|September 22, 2000
PubMed
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Topical iodine antiseptics in obstetrics and neonatology cause iodine overload in mothers and newborns. This overload can disrupt thyroid function, leading to false positives in congenital hypothyroidism screening and potential harm to neonates.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatology
  • Endocrinology

Context:

  • Iodine-containing antiseptics are frequently used in perinatal care.
  • Transdermal absorption of iodine is rapid in both mothers and neonates.
  • Iodine overload occurs in mothers via maternal administration and in neonates via direct application and breastfeeding.

Purpose:

  • To highlight the issue of iodine overload from antiseptic use in obstetrics and neonatology.
  • To discuss the physiological consequences of iodine overload in the perinatal period.
  • To advocate for the avoidance of iodine antiseptics during childbirth and in newborns.

Summary:

  • Topical iodine antiseptics administered to mothers and newborns lead to significant iodine overload.
  • Maternal and neonatal iodine levels increase substantially, impacting thyroid function.

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  • This overload can cause thyroid blockade, affecting congenital hypothyroidism screening and potentially harming neonates.
  • Impact:

    • Iodine overload can result in false positives in newborn screening for congenital hypothyroidism, increasing parental anxiety and healthcare costs.
    • The thyroid blockade effect poses serious risks to neonatal health.
    • Recommends avoiding iodine antiseptics in the perinatal period to prevent adverse effects.