Related Experiment Videos
Self-assembly and lyomesophases formed by long-chain alkoxymethyl-nucleobase derivatives
W V Meister1, S Lindau, C Bohley
1Martin Luther University Halle-Wittenberg, Institute of Biochemistry, Halle, Saale, Germany. meister@biochemtech.uni-halle.de
Nucleosides, Nucleotides & Nucleic Acids
|September 22, 2000
Abstract:
Amphiphilic complementary nucleobase derivatives, containing n-octadecyloxymethyl substituents at the N1 position of pyrimidine and N9 of purine, dissolved in chloroform form non-specific lyotropic mesophases, which were analyzed by optical polarizing microscopy. Molecular modeling studies visualize hypothetical horizontal and vertical nucleobase hydrogen-bonding and stacking arrangements, as well as aliphatic long-chain interstrand interaction.