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[Lipid profile in children from Rivas-Vaciamadrid. Two-year follow-up]
M J Peláez Gómez de Salazar1, M Sánchez Bayle, A González-Requejo
1Centro de Salud de Rivas-Vaciamadrid. Hospital del Niño Jesús. Madrid.
Insights
This study tracked children's lipid profiles for two years. Lipid levels and indices improved, particularly in boys, showing a correlation with initial measurements.
Area of Science:
- Pediatric lipidology
- Cardiovascular risk assessment in children
Context:
- Understanding childhood lipid profiles is crucial for long-term cardiovascular health.
- Longitudinal data on pediatric lipid parameters and their changes over time are limited.
Purpose:
- To evaluate changes in lipid profiles and related indices in children over a two-year follow-up period.
- To assess the correlation between baseline and follow-up lipid measurements in a pediatric cohort.
Summary:
- A two-year longitudinal study followed children from age six, analyzing total cholesterol, triglycerides, LDL, HDL, apoproteins A and B, and various ratios.
- Lipid profiles and indices showed improvement over the follow-up period, with statistically significant changes noted primarily in males.
- A significant correlation was observed between initial lipid profile values at age six and those measured after two years.
Impact:
- Provides valuable insights into the dynamic nature of lipid profiles during childhood.
- Highlights potential sex-based differences in lipid profile development and response to follow-up.
- Informs early identification and management strategies for dyslipidemia in pediatric populations.
Aim:
Evaluate the lipid profiles in children after two years of follow-up.
Methods:
Longitudinal cohort study. A two years follow-up of a group of children since they were 6 years old. Blood analysis were carried in every children measuring total cholesterol, triglycerides, cLDL, cHDL, apoproteins A and B. It also included TD/cHDL, cLDL/cHDL, Apo B/A ratios and atherogenic index.
Results:
200 mg/dl, cLDL > 135 mg/dl and Apo B > 100 mg/dl in the follow-up was of 9.51, 5.18 and 8 for those children who had in the initial study these same values. The values of lipid profile and of the index studied improved in the two years of follow-up. This improvement has an statistical signification only in men.
Conclusions:
There is a significant correlation between the values of the lipid profile and the index measured in those children who were six years old in the beginning of the two years follow-up.