[Can vesicoureteral reflux be predicted in infants with urinary infection?]

M Sánchez Bayle1, G Yep Chullen, E de La Torre Montes de Neira

  • 1Sección de Lactantes, Hospital Niño Jesús, Madrid. msanba@teleline.es

Insights

Predicting vesicoureteral reflux (VUR) in infants after their first urinary tract infection (UTI) is possible. Renal ultrasound anomalies and non-E. coli UTI significantly indicate VUR presence and severity.

Area of Science:

  • Pediatric Nephrology
  • Diagnostic Imaging
  • Infectious Diseases

Context:

  • Infantile urinary tract infections (UTIs) are common.
  • Vesicoureteral reflux (VUR) is a significant risk factor for renal scarring.
  • Accurate prediction of VUR in infants is crucial for timely intervention.

Purpose:

  • To develop a predictive formula for VUR in infants experiencing their first UTI.
  • To identify key indicators for VUR presence and severity.

Summary:

  • A study of 267 infants with first UTIs analyzed renal ultrasound, VCUG, and CRP results.
  • Multivariable analysis identified renal ultrasound anomalies and non-E. coli UTI as significant predictors of VUR.
  • Oostenbruck's score was found to be ineffective for VUR detection.

Impact:

  • Findings suggest limiting voiding cystourethrogram (VCUG) indications to infants with renal ultrasound anomalies or non-E. coli UTIs.
  • This approach may optimize diagnostic workups for first-time UTIs in infants.
  • Further research is needed to validate these predictive factors.
Abstract

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