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Cocaine-associated ischemic colitis.

J D Linder1, K E Mönkemüller, I Raijman

  • 1Department of Medicine, University of Alabama at Birmingham, USA.

Southern Medical Journal
|September 27, 2000
PubMed
Summary
This summary is machine-generated.

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Cocaine use can cause serious gastrointestinal problems, including ischemic colitis. This condition, characterized by abdominal pain and bloody diarrhea, requires prompt medical attention, especially in young to middle-aged adults.

Area of Science:

  • Gastroenterology
  • Toxicology

Background:

  • Cocaine use is associated with diverse gastrointestinal complications.
  • These can range from ulcerations to perforation and ischemia.

Observation:

  • This report details three cases of cocaine-associated colonic ischemia.
  • A literature review identified a total of 28 reported cases.

Findings:

  • The mean age of affected patients was 32.6 years, with a near-equal gender distribution.
  • Symptom onset typically occurred within 1-2 days of cocaine ingestion.

Implications:

  • Cocaine-induced ischemic colitis is a critical diagnosis in young to middle-aged adults presenting with abdominal pain and bloody diarrhea.
  • It should be considered in the differential diagnosis, particularly when common causes like estrogen use or thromboembolic disorders are absent.

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