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Bioactive macroporous titanium surface layer on titanium substrate.

H M Kim1, T Kokubo, S Fujibayashi

  • 1Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. kim@sung7.kuic.kyoto-u.ac.jp

Journal of Biomedical Materials Research
|September 28, 2000
PubMed
Summary
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Treating macroporous titanium implants with sodium hydroxide (NaOH) and heat creates a bioactive surface. This enhanced surface promotes bone ingrowth and chemical integration for improved implant fixation.

Area of Science:

  • Biomaterials Engineering
  • Orthopedic Implants
  • Surface Chemistry

Background:

  • Macroporous titanium surfaces enhance implant fixation through bone ingrowth.
  • Titanium's bioactivity can be significantly increased through specific chemical and thermal treatments.

Purpose of the Study:

  • To investigate the effects of sodium hydroxide (NaOH) and heat treatments on macroporous titanium surfaces.
  • To determine if these treatments enhance the bioactivity and bone integration potential of porous titanium implants.

Main Methods:

  • Applied 5.0 M-NaOH treatment (60°C for 24h) followed by heat treatment (600°C for 1h) to plasma-sprayed macroporous titanium.
  • Analyzed the surface morphology and composition using techniques suitable for porous structures.
  • Assessed apatite formation in simulated body fluid (SBF) to evaluate bioactivity.

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Main Results:

  • NaOH and heat treatments formed a uniform amorphous sodium titanate layer on the macroporous titanium surface.
  • The sodium titanate layer induced rapid and uniform bonelike apatite formation in SBF.
  • Apatite layer growth occurred along the surface and within the cross-sectional macrotextures of the porous titanium.

Conclusions:

  • NaOH and heat treatments render macroporous titanium surfaces bioactive.
  • The bioactive surface promotes enhanced bony ingrowth into the porous structure.
  • The apatite layer facilitates chemical integration with bone, improving implant osseointegration.