Related Experiment Video
Updated: Jun 26, 2026
Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
Published on: March 1, 2016
Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its
Zuwei Ma1, Changyou Gao, Yihong Gong
1Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
Abstract:
With the use of a grafting-coating method, three kinds of natural macromolecules, that is, gelatin, collagen, or chitosan, were immobilized on poly-L-lactic acid (PLLA) membrane surfaces with the goal of improving of cellular interactions. Attenuated total reflectance infrared spectroscopy (ATR-IR), x-ray photoelectron spectroscopy (XPS) and surface morphology analysis using scanning electronic microscopy (SEM) confirmed that the natural macromolecule layers adhered tightly to the hydrophobic PLLA membrane surfaces. Chondrocyte culture showed that the modified PLLA membranes had higher cell attachment, higher cell proliferation rate, and higher cell activity than the control PLLA membrane. Moreover, the chondrocytes were more spread out on the modified PLLA membranes than on the control PLLA membranes.
More Related Videos
12:22Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
Published on: October 26, 2016
06:15Wet Chemistry and Peptide Immobilization on Polytetrafluoroethylene for Improved Cell-adhesion
Published on: August 15, 2016