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[Wolfram syndrome. Urologic implications]
F J Anglada Curado1, M Leva Vallejo, A Blanco Espinosa
1Servicio de Urología, Hospital Regional Universitario Reina Sofía, Córdoba.
Objectives:
We report on four new cases of Wolfram's Syndrome. We emphasize in urological aspects of this disease.
Patients And Methods:
Three male siblings. The other patient is also a male, without familiar relation with the other ones. All four patients presents different levels of urological alterations, mainly urinary collecting system dilation and decrease in detrusor muscle contractility.
Conclusions:
Urological findings are cardinal aspects in Wolfram syndrome. Due to its high frequency and prognostic value in natural history of disease. Urological disease seems to be within a systemic neurological tissues affectation of etiology that remains unknown.