Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiomyopathy in AIDS: a pathophysiological perspective.

W Lewis1

  • 1Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA. wlewis@emory.edu

Progress in Cardiovascular Diseases
|October 3, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Testicular torsion treatment: the horns of a dilemma?

Annals of the Royal College of Surgeons of England·2019
Same author

Synthesis of malhamensilipin A exploiting iterative epoxidation/chlorination: experimental and computational analysis of epoxide-derived chloronium ions.

Chemical science·2017
Same author

Electron-scale measurements of magnetic reconnection in space.

Science (New York, N.Y.)·2016
Same author

HIV, highly active antiretroviral therapy and the heart: a cellular to epidemiological review.

HIV medicine·2015
Same author

Facile access to a heterocyclic, sp(3)-rich chemical scaffold via a tandem condensation/intramolecular nitrone-alkene [3+2] cycloaddition strategy.

Chemical communications (Cambridge, England)·2015
Same author

Dilated cardiomyopathy in a zidovudine-treated AIDS patient.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same journal

Mavacamten and left ventricular dysfunction in hypertrophic cardiomyopathy with left bundle branch block.

Progress in cardiovascular diseases·2026
Same journal

Coronary artery Ectatic/Aneurysmatic disease: From pathophysiology to management.

Progress in cardiovascular diseases·2026
Same journal

Comparative associations of LDL-C, Lp(a), hsCRP, and IL-6 with cardiovascular risk: Insights from the United Kingdom (UK) biobank and the multi-ethnic study of atherosclerosis (MESA).

Progress in cardiovascular diseases·2026
Same journal

Effect of physical exercise-based cardiac rehabilitation on frail patients with heart failure: focus on endothelial dysfunction.

Progress in cardiovascular diseases·2026
Same journal

The impact of Corona virus disease - 2019 on coronary atherosclerosis: Rationale and design of the COrona VIrus Disease-2019 computed tomography (COVID-CT) registry.

Progress in cardiovascular diseases·2026
Same journal

Lipoprotein(a), remnant cholesterol, and high-sensitivity C-reactive protein as complementary biomarkers for myocardial infarction risk assessment.

Progress in cardiovascular diseases·2026
See all related articles

Cardiomyopathy in acquired immunodeficiency syndrome (AIDS) is increasingly recognized. Effective antiretroviral therapy contributes to its rising prevalence, driven by multifactorial causes including comorbidities and treatment toxicity.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Immunology

Background:

  • Acquired immunodeficiency syndrome (AIDS) survival is improving with advanced antiretroviral therapy.
  • Cardiomyopathy is an emerging complication in the growing population of individuals with AIDS.
  • Understanding AIDS-related cardiomyopathy is crucial due to increased patient longevity.

Purpose of the Study:

  • To review the pathogenesis, pathophysiology, and epidemiology of cardiomyopathy in AIDS.
  • To explore the complex interplay of factors contributing to AIDS-related cardiomyopathy.
  • To highlight the multifactorial nature of this cardiac condition.

Main Methods:

  • Literature review of cellular and organism factors in AIDS.
  • Analysis of comorbid conditions associated with AIDS.

Related Experiment Videos

  • Examination of inflammatory, vascular, myocardial, and retroviral roles.
  • Assessment of antiretroviral therapy toxicity impact.

    • Main Results:

    • Comorbid conditions are frequently observed in AIDS patients.
    • Inflammatory heart disease and cytokines play a role in AIDS cardiomyopathy.
    • Vascular and myocardial cells, myocardial retroviral infection, and antiretroviral toxicity are implicated.
    • Multiple contributing factors likely coexist in individual patients.

    Conclusions:

    • AIDS-related cardiomyopathy is a multifactorial condition.
    • Increased patient survival necessitates attention to cardiac health in AIDS.
    • Further research into the complex pathogenesis is warranted.