DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking.

T B Geijtenbeek1, D J Krooshoop, D A Bleijs

  • 1Department of Tumor Immunology, University Medical Center St Radboud, Philips van Leydenlaan 25, Nijmegen 6525 EX, The Netherlands.

Nature Immunology
|March 23, 2001
PubMed
Summary

Dendritic cells (DCs) use DC-SIGN to attach to ICAM-2 on blood vessels, enabling their crucial migration from blood into tissues to fight infections.

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