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Evolution of nutritional status of infants infected with the human immunodeficiency virus

V A Leandro-Merhi1, M M Vilela, M N Silva

  • 1Department of Nutrition, Pontifícia Universidade Católica de Campinas, Campinas, Brazil.

Sao Paulo Medical Journal = Revista Paulista De Medicina
|October 6, 2000
PubMed

Insights

Human immunodeficiency virus (HIV) infection significantly impacts infant growth. Infected infants show severely affected growth parameters compared to non-infected infants, with changes beginning early in life.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Nutritional Science

Background:

  • Limited studies exist on growth and nutritional status in children with HIV.
  • Understanding these parameters is crucial for early intervention and management.

Purpose of the Study:

  • To investigate the nutritional status and growth patterns of infants infected with human immunodeficiency virus (HIV).

Main Methods:

  • A longitudinal study evaluated 124 infants born to HIV-infected mothers from birth to two years.
  • Participants were divided into HIV-infected (n=71) and non-infected (n=53) groups.
  • Growth was assessed using Z-scores for weight-for-age, length-for-age, and weight-for-length, referencing NCHS curves.

Main Results:

  • Significant differences in growth Z-scores were observed between infected and non-infected groups for most variables.
  • Exceptions included length-for-age at 3 months and weight-for-length at 21 months (P > 0.05).

Conclusions:

  • HIV infection severely impairs infant growth compared to seroreversed infants.
  • Growth alterations commence early post-birth, preceding clinical manifestations.
Abstract

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