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[Platelet aggregation in patients with hypertrophic cardiomyopathy]
Terapevticheskii Arkhiv
|October 6, 2000
Abstract
Aim:
To examine correlation between platelet aggregation and the degree of left ventricular hypertrophy (LVH) in patients with hypertrophic cardiomyopathy (HC).
Material And Methods:
Routine clinical examination, ECG, echo-CG, measurement of platelet aggregation, routine biochemical blood tests were made in 45 HC males and 15 healthy controls.
Results:
HC patients were characterized with high induced and spontaneous platelet aggregation which increased with left ventricular myocardial mass. In LVH, platelets were especially sensitive to the aggregation inductor U-46619, thromboxane A2 analogue.
Conclusion:
It is demonstrated that there is a positive correlation between platelet aggregation and the degree of LVH in HC patients.