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Mortality Trend of Cerebrovascular Disorders: A Cross-sectional Study in Northern Iran (2016-2023)

Amirhossein Alizadeh-Nodehi1, Mohammad-Ali Jahani2, Pouyan Ebrahimi3,4

  • 1Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Archives of Iranian Medicine
|August 16, 2026
PubMed

Insights

Mortality from cerebrovascular disorders (CeVDs) significantly decreased in northern Iran from 2016-2023. Despite overall improvements, rural death rates remain a concern, requiring targeted interventions.

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • Cerebrovascular disorders (CeVDs) represent a major global health challenge, contributing significantly to worldwide mortality.
  • Understanding regional mortality trends is crucial for effective public health strategies.

Purpose of the Study:

  • To analyze temporal trends in mortality rates associated with cerebrovascular disorders (CeVDs) in northern Iran.
  • To assess changes in CeVDs mortality between 2016 and 2023.

Main Methods:

  • A cross-sectional study design was employed, analyzing all documented CeVD deaths in Babol County from 2016 to 2023.
  • Crude mortality rate (CMR) and age-standardized mortality rate (ASMR) were calculated.
  • Cochran-Armitage trend test and Joinpoint regression were utilized to analyze mortality trends.

Main Results:

  • A total of 1,798 CeVD deaths were recorded, with a mean age of 76.8 years.
  • Both CMR and ASMR showed a significant decline from 2016 to 2023 (P<0.001).
  • Joinpoint regression identified 2018 as a breakpoint, with ASMR decreasing by -7.98% annually from 2018-2023.

Conclusions:

  • A notable reduction in CeVD mortality was observed, suggesting advancements in treatment and care.
  • Persistent high mortality rates in rural populations necessitate focused public health interventions.
  • Increased resource allocation and tailored strategies are essential for addressing CeVDs, particularly in underserved areas.
Abstract

Keywords:
Cerebrovascular disordersIranJoinpoint regressionStroke

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