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Rectal function following prostate brachytherapy.

G S Merrick1, W M Butler, A T Dorsey

  • 1Schiffler Oncology Center, Wheeling Hospital, Wheeling, WV 26003-6300, USA. oncology@hgo.net

International Journal of Radiation Oncology, Biology, Physics
|October 6, 2000
PubMed
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Prostate brachytherapy patients experienced minor bowel function changes, with less than 20% reporting worsening symptoms. Late bowel function after prostate brachytherapy remains largely unaffected.

Area of Science:

  • Oncology
  • Radiation Oncology
  • Urology

Background:

  • Quality of life after prostate cancer treatment is crucial.
  • Bowel function data post-prostate brachytherapy is limited.
  • Assessing late bowel function is important for patient well-being.

Purpose of the Study:

  • To evaluate late bowel function in patients after prostate brachytherapy.
  • To identify factors influencing bowel dysfunction post-treatment.
  • To document the impact of prostate brachytherapy on rectal function.

Main Methods:

  • A questionnaire assessed late bowel function in 209 prostate brachytherapy patients (16-55 months post-implant).
  • Compared outcomes with 30 newly diagnosed prostate cancer patients as controls.

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  • Analyzed clinical and treatment parameters for correlation with bowel dysfunction.

    • Main Results:

    • Brachytherapy patients reported significantly worse bowel function scores than controls (4.3 vs. 1.6, p < 0.001).
    • Only pre-implant bowel movement frequency correlated with post-treatment scores.
    • Less than 20% of patients reported worsening bowel function; external beam radiation therapy negatively impacted perceived rectal quality of life.

    Conclusions:

    • Prostate brachytherapy generally results in minor, non-severe late bowel function changes.
    • Most patients do not experience significant bother from post-brachytherapy bowel changes.
    • While bowel function scores are higher post-implant, the clinical impact is minimal for most individuals.