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(5S)-3-oxo-4-oxa-endo-tricyclo[5.2.1.0(2,6)]dec-8-en-5-yl acetate
1Bijvoet Centre for Biomolecular Research, Department of Crystal and Structural Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. d.d.ellis@chem.uu.nl.
Acta Crystallographica. Section C, Crystal Structure Communications
|October 12, 2000
Summary
Researchers confirmed the molecular structure of a norbornene derivative, C(11)H(12)O(4), detailing its acetoxy side-chain configuration and endo product formation. This structural elucidation provides key insights into the molecule
Area of Science:
- Organic Chemistry
- Stereochemistry
- Crystallography
Background:
- Norbornene derivatives are important scaffolds in organic synthesis.
- Understanding the stereochemical outcome of reactions is crucial for developing new synthetic methodologies.
Purpose of the Study:
- To establish the precise molecular structure of C(11)H(12)O(4).
- To confirm the stereochemical configuration of an acetoxy side-chain group.
- To verify the formation of the endo product.
Main Methods:
- X-ray crystallography was employed to determine the molecular structure.
- Analysis of bond distances and angles provided geometric parameters.
- Chiral starting materials were used to ascertain overall stereochemistry.
Main Results:
- The molecular structure of C(11)H(12)O(4) was definitively established.
- The acetoxy side chain was confirmed to be in an axial position.
- Geometric parameters were found to be within expected ranges, indicating no unusual structural features.
- The endo product formation was confirmed.
Conclusions:
- The study successfully elucidated the molecular structure and stereochemistry of the norbornene derivative.
- The findings confirm the axial orientation of the acetoxy group and the formation of the endo product.
- This detailed structural information is valuable for future synthetic endeavors involving similar norbornene scaffolds.