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A neurobiologically informed perspective on psychotherapy.

G O Gabbard1

  • 1Karl Menninger School of Psychiatry, Topeka, KS, USA. gabbargo@menninger.edu

The British Journal of Psychiatry : the Journal of Mental Science
|October 12, 2000
PubMed
Summary

Psychotherapy measurably alters brain function by influencing gene expression and implicit memory. This neuroscience-informed approach heralds a new era for targeted psychological treatments.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Psychology

Background:

  • Psychiatry's historical division between biological and psychosocial factors created Cartesian dualism.
  • Integrating biological and psychological knowledge enables a holistic treatment approach.

Purpose of the Study:

  • To explore conceptual models of how psychotherapy impacts brain function.
  • To review the interplay between genetics and environment in psychiatric contexts.

Main Methods:

  • Surveying literature on gene-environment interactions.
  • Reviewing research on psychotherapy's effects on the brain.

Main Results:

  • The brain modifies gene expression in response to environmental stimuli.

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  • Psychotherapy demonstrates specific, quantifiable effects on brain activity.
  • Psychotherapeutic interventions can alter implicit memory.

    • Conclusions:

    • Neuroscience advances deepen the understanding of psychotherapy's brain effects.
    • This knowledge facilitates the development of psychotherapy tailored to specific brain functions.
    • A new era of psychotherapy research and practice is emerging.