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Updated: Aug 8, 2026

Protein Misfolding Cyclic Amplification of Prions
10:12

Protein Misfolding Cyclic Amplification of Prions

Published on: November 7, 2012

Copper refolding of prion protein

B S Wong1, C Vénien-Bryan, R A Williamson

  • 1School of Animal and Microbial Sciences, Reading, RG6 6AH, United Kingdom.

Biochemical and Biophysical Research Communications
|October 12, 2000
PubMed
Summary

Copper binding to mouse prion protein (MoPrP) enhances its antioxidant activity by altering its structure. This copper-bound MoPrP exhibits increased stability and requires the disulfide bond for full antioxidant function.

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