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[Update endocrinology I (Neuroendocrinology)]
A Hanisch1, H Lehnert, J Hensen
1Klinik für Endokrinologie und Stoffwechselkrankheiten, Otto-von-Guericke-Universität Magdeburg.
Medizinische Klinik (Munich, Germany : 1983)
|October 12, 2000
Summary
This review covers neuroendocrinology, focusing on pituitary disorders. It details pathogenesis, therapeutic strategies, and growth hormone replacement in adults.
Area of Science:
- Neuroendocrinology
- Pituitary Gland Biology
Context:
- Current understanding of hypothalamic and pituitary regulation.
- Focus on the intrapituitary network of cytokines, growth factors, and gaseous transmitters.
- Exploration of the interleukin-6 family's role in pituitary function.
Purpose:
- To provide an overview of pituitary disorder pathogenesis and therapeutic strategies.
- To discuss the molecular basis of pituitary adenomas, including familial syndromes.
- To present advancements in medical, surgical, and radiation therapy for pituitary adenomas, with a future outlook on gene therapy.
Summary:
- Details the intricate regulation of the anterior pituitary by intrapituitary signaling networks.
- Reviews the molecular pathogenesis of pituitary adenomas and associated familial syndromes.
- Highlights recent therapeutic developments and future prospects, including gene therapy and growth hormone replacement.
Impact:
- Informs researchers and clinicians on the latest neuroendocrine research.
- Facilitates understanding of pituitary adenoma development and treatment options.
- Provides a comprehensive resource for pituitary disorder management and future research directions.