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Validation of the side effect and life satisfaction (SEALS) inventory
R Gillham1, L Bryant-Comstock, K Kane
1Southern General Hospital, Glasgow, Scotland, UK. RuthGillham@Compuserve.com
Seizure
|October 18, 2000
Summary
The Side Effect and Life Satisfaction (SEALS) inventory effectively measures patient satisfaction with antiepileptic drug (AED) therapy. This validated tool aids in managing epilepsy and improving quality of life (QOL) for patients.
Area of Science:
- Neurology
- Psychometrics
- Clinical Pharmacology
Background:
- Epilepsy significantly impacts quality of life (QOL), even with controlled seizures.
- Antiepileptic drug (AED) therapy is a key factor influencing health-related quality of life (HRQOL).
- A validated instrument is needed to assess AED therapy's impact on patients.
Purpose of the Study:
- To evaluate the construct validity of the Side Effect and Life Satisfaction (SEALS) inventory.
- To establish SEALS as a reliable tool for measuring satisfaction with AED therapy.
Main Methods:
- The SEALS inventory was administered to 307 epilepsy patients.
- Construct validity was assessed by comparing SEALS with POMS, HAD, and MOS-COG scales.
- Pearson's correlation coefficients were calculated to analyze relationships between instruments.
Main Results:
- The SEALS inventory demonstrated statistically significant correlations with established psychometric instruments.
- These findings support the construct validity of the SEALS inventory.
Conclusions:
- The SEALS inventory is a valid and efficient psychometric tool for assessing satisfaction with AED therapy.
- SEALS is suitable for clinical trials and long-term epilepsy management.
- This instrument can help improve patient QOL by informing AED therapy decisions.