Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gabapentin-induced mood changes with hypomanic features in adults.

E Trinka1, U Niedermüller, C Thaler

  • 1Universitätsklinik für Neurologie Innsbruck, Austria.

Seizure
|October 18, 2000
PubMed
Summary

Gabapentin (GBP) can cause behavioral side effects like euphoria and increased energy in adults. These effects are reversible, but may require discontinuing GBP treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Level of consciousness, wakefulness and responsiveness in epileptic seizures.

Revue neurologique·2026
Same author

Exploring the link between socioeconomic factors and rheumatoid arthritis: Insights from a large Austrian study.

Annals of epidemiology·2025
Same author

Seminars in epileptology: How to diagnose status epilepticus in adults and children.

Epileptic disorders : international epilepsy journal with videotape·2025
Same author

Successful use of fenfluramine in drug resistant epileptic encephalopathy with spike-wave activation in sleep (EE-SWAS)- an automated EEG study.

Seizure·2025
Same author

Brain damage caused by status epilepticus: A prospective MRI study.

Epilepsy & behavior : E&B·2024
Same author

Progesterone and its derivatives for the treatment of catamenial epilepsy: A systematic review.

Seizure·2023

Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Gabapentin (GBP) is a medication prescribed for epilepsy and neuropathic pain.
  • Behavioral side effects of GBP in adults are not well-documented.

Observation:

  • Two adult patients developed behavioral changes after initiating GBP therapy.
  • Neither patient had a prior history of psychiatric or behavioral disorders.

Findings:

  • Observed side effects included elevated mood, euphoria, increased energy, pressured speech, and decreased need for sleep.
  • Symptoms were transient and fully reversible upon GBP discontinuation in one case.
  • Behavioral changes were independent of seizure activity.

Implications:

  • Clinicians should be aware of potential behavioral side effects associated with gabapentin use in adults.

Related Experiment Videos

  • Monitoring for mood and behavioral changes is recommended during GBP treatment.
  • These findings contribute to understanding the broader side effect profile of gabapentin.