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Psoriatic eruption in Kawasaki disease
B A Eberhard1, R P Sundel, J W Newburger
1Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
The Journal of Pediatrics
|October 18, 2000
Summary
Kawasaki disease can trigger psoriatic skin rashes in children. These typically psoriasiform or pustular eruptions resolved without progressing to chronic psoriasis in observed patients.
Area of Science:
- Dermatology
- Pediatrics
- Rheumatology
Background:
- Kawasaki disease is an acute febrile illness affecting young children.
- Cutaneous manifestations are common in Kawasaki disease, but psoriatic eruptions are rare.
- The association between Kawasaki disease and psoriasis requires further investigation.
Purpose of the Study:
- To report on the occurrence of psoriatic skin lesions in patients with Kawasaki disease.
- To characterize the clinical presentation and evolution of these skin eruptions.
- To determine if these eruptions predict the development of chronic psoriasis.
Main Methods:
- Case series describing 10 pediatric patients.
- Clinical observation of skin lesions during acute and convalescent phases of Kawasaki disease.
- Follow-up to assess for chronic psoriasis development.
Main Results:
- Ten patients developed psoriatic skin eruptions during Kawasaki disease.
- Lesions were pustular in 3 patients and psoriasiform in 7 patients.
- No patients progressed to chronic psoriasis during the observation period.
Conclusions:
- Psoriatic skin eruptions can be a transient manifestation of Kawasaki disease.
- These eruptions do not appear to predict the development of chronic psoriasis.
- Further research is needed to understand the immunopathogenesis of this association.
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