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[Prevalence of congenital malformations]

B A Voĭtsekhovich, L G Teslenko

    Problemy Sotsial'Noi Gigieny, Zdravookhraneniia I Istorii Meditsiny
    |October 19, 2000
    PubMed

    Insights

    Hereditary diseases in Krasnodar children increased from 1987-1998, impacting life span and neonatal mortality. This trend is linked to worsening socioeconomic and environmental factors.

    Area of Science:

    • Pediatrics
    • Public Health
    • Genetics

    Background:

    • The period 1987-1998 in Krasnodar saw significant socioeconomic changes impacting public health.
    • Congenital malformations and hereditary diseases represent a notable public health concern in pediatric populations.

    Purpose of the Study:

    • To analyze the incidence of congenital malformations in children.
    • To investigate the relationship between hereditary diseases and average life span.
    • To assess morbidity, death/birth rate, and neonatal mortality due to hereditary diseases in Krasnodar.

    Main Methods:

    • Retrospective analysis of epidemiological data from Krasnodar (1987-1998).
    • Focus on congenital malformations, hereditary diseases, and associated mortality rates.
    • Correlation analysis between disease incidence, life span, and socioeconomic/environmental factors.

    Main Results:

    • An increasing incidence of hereditary diseases incompatible with life was observed.
    • A correlation was found between hereditary diseases and reduced average life span.
    • Elevated morbidity and neonatal mortality rates linked to hereditary diseases were documented.

    Conclusions:

    • The rising incidence of severe hereditary diseases poses a significant threat to child survival.
    • Deteriorating socioeconomic conditions, communal living, and environmental factors are likely drivers of this increase.
    • Urgent public health interventions are needed to address the growing burden of hereditary diseases.

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