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[Pacinian neurofibroma of the vulva]
M Medina Perez1, E Rafel Ribas, J A Valero Puerta
1Servicio de Anatomica Patológica, Hospital de la Merced, Osuna, Sevilla, España. mediosun@arrakis.es
Objective:
To report on a rare case of Pacinian neurofibroma of the vulva.
Methods:
A 27-year-old patient who presented with a vulvar tumor is described. Patient evaluation showed no other remarkable findings.
Results:
The nodule was resected without difficulty. The histopathological analysis-demonstrated Pacinian neurofibroma with abundant concentric laminar structures. The immunohistochemical (CD34+), ultrastructural and histological analyses showed perineural cells. No signs of neurofibromatosis were found.
Conclusions:
Pacinian neurofibroma may present in the vulva and could probably arise from the so-called perineural fibroblasts.