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Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells
M A Higman1, J D Port, N J Beauchamp
1Departments of Oncology and Pediatrics, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Bone Marrow Transplantation
|October 24, 2000
Abstract:
We report a case of posterior reversible leuko- encephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing's sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months. Bone Marrow Transplantation (2000) 26, 797-800.