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Massive bleeding from colonic diverticular disease with NSAID use
A Muthu1, A Qureshi, M A Ismail
1Department of Surgery, Hospital UKM, Cheras, Kuala Lumpur.
The Medical Journal of Malaysia
|October 25, 2000
Summary
Non-steroidal anti-inflammatory drugs (NSAID) can cause severe rectal bleeding, especially in patients with diverticular disease. This case highlights NSAID
Area of Science:
- Gastroenterology
- Colorectal Surgery
Background:
- Non-steroidal anti-inflammatory drugs (NSAID) are widely used for pain and inflammation.
- NSAID use is a known risk factor for upper gastrointestinal bleeding.
- Complications of NSAID in the lower gastrointestinal tract, particularly with diverticular disease, are less understood.
Observation:
- A 58-year-old male presented with severe per rectal bleeding.
- The patient had a history of diverticular disease.
- NSAID use was identified as a potential contributing factor.
Findings:
- NSAID can exacerbate or trigger lower gastrointestinal bleeding in patients with diverticular disease.
- Diverticular bleeding can be severe and life-threatening.
- Cessation of NSAID may be crucial in managing such cases.
Implications:
- Clinicians should consider NSAID as a potential cause of lower gastrointestinal bleeding in patients with diverticular disease.
- Patient education regarding NSAID risks in the context of diverticular disease is important.
- Further research is needed to elucidate the mechanisms of NSAID-induced diverticular complications.