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Construction of chiral 1,2-cycloalkanopyrrolidines from L-proline using ring closing metathesis (RCM)
M Arisawa1, M Takahashi, E Takezawa
1Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Chemical & Pharmaceutical Bulletin
|October 25, 2000
Abstract:
An efficient synthetic method for the preparation of optically active pyrroloazocine, pyrroloazepine, quinolizidine, indolizidine using ring closing olefin metathesis (RCM) is described.