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Related Experiment Videos

Pulmonary tuberculosis: CT and pathologic correlation.

J Y Lee1, K S Lee, K J Jung

  • 1Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Journal of Computer Assisted Tomography
|October 25, 2000
PubMed
Summary

Computed tomography (CT) reveals distinct patterns for active and inactive pulmonary tuberculosis. These imaging findings correlate with underlying histopathology, aiding diagnosis in typical and atypical cases.

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Area of Science:

  • Radiology
  • Pulmonology
  • Pathology

Background:

  • Pulmonary tuberculosis (TB) diagnosis relies on characteristic imaging findings.
  • Computed tomography (CT) provides detailed visualization of TB manifestations.
  • Understanding CT patterns is crucial for differentiating active from inactive disease.

Purpose of the Study:

  • To delineate typical and atypical CT findings in primary, postprimary, and miliary tuberculosis.
  • To correlate CT appearances with underlying histopathologic features.
  • To enhance diagnostic accuracy of pulmonary TB through radiologic interpretation.

Main Methods:

  • Review of CT scans from patients with confirmed pulmonary tuberculosis.
  • Analysis of imaging features including nodules, consolidation, cavitation, and lymphadenopathy.

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  • Correlation of radiologic findings with histopathologic diagnoses.

    • Main Results:

    • Active postprimary TB: centrilobular nodules, tree-in-bud, consolidation, cavitation.
    • Inactive TB: calcified lesions, linear opacities, fibrosis, emphysema.
    • Primary TB: lobar consolidation, hilar/mediastinal lymphadenopathy.
    • Atypical findings: nodules/masses, basilar infiltrates, miliary patterns, cysts.
    • Histopathology: caseating granulomas (active), fibrosis/calcification (inactive).

    Conclusions:

    • CT imaging demonstrates diverse patterns for pulmonary tuberculosis.
    • Distinct CT features differentiate active from inactive disease stages.
    • Radiologic findings correlate with histopathologic basis, aiding diagnosis.