Related Experiment Video
Updated: Jul 25, 2026

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
Published on: June 20, 2019
Early stages of homopolymer collapse
1UMR 5819 (CEA-CNRS-UJF), DRFMC, CEA-Grenoble, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France.
Abstract:
Interest in the protein folding problem has motivated a wide range of theoretical and experimental studies of the kinetics of the collapse of flexible homopolymers. In this paper, a phenomenological model is proposed for the kinetics of the early stages of homopolymer collapse following a quench from temperatures above to below the straight theta temperature. In the first stage, nascent droplets of the dense phase are formed, with little effect on the configurations of the bridges that join them. The droplets then grow by accreting monomers from the bridges, thus causing the bridges to stretch. During these two stages, the overall dimensions of the chain decrease only weakly. Further growth of the droplets is accomplished by the shortening of the bridges, which causes the shrinking of the overall dimensions of the chain. The characteristic times of the three stages scale as N0, N(1/5), and N(6/5), respectively, where N is the degree of polymerization of the chain.
Related Concept Videos
Polymers
Polymers
Radical Chain-Growth Polymerization: Mechanism
Step-Growth Polymerization: Overview
Many natural and synthetic polymers are produced by...
Molecular Weight of Step-Growth Polymers
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
Polymers

