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Updated: Oct 2, 2026

Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method
Published on: May 14, 2009
[Measurement of arterial pressure with a mercury sphygmomanometer more than a technique]
1Klinika za unutrasnje bolesti Medicinskog fakulteta Sveucillsta u Zagrebu i Klinickog bolnickog centra Zagreb.
Abstract:
Arterial blood pressure has been measured using mercury sphygmomanometer and auscultatory method for more than a hundred years. The results obtained by this measurement method make the basis of almost all conclusions related to pathogenesis, epidemiology and treatment of arterial hypertension. However, some deviations from ordinarily obtained data have been observed but are undoubtedly due to superficial approach to this simple method. A number of lesser faults can together result in an eventually inaccurate conclusion both regarding diagnosis and assessment of therapeutic effects. The aim of this short review article is to remind us of those little efforts needed to be done for improving the exactness of measurement in order to increase the accuracy of results. The ultimate consequence should be better care of patients with high blood pressure.
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This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
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Prepare for the Procedure:
Assessment of blood pressure in brachial artery(two-step method)
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