Related Experiment Video
Updated: Aug 2, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
Published on: April 23, 2014
[Do cognitive deficits in depressive disorders remit?]
K Frasch1, S Bretschneider, C Bullacher
1Bezirkskrankenhaus Günzburg.
Objective:
The importance of cognitive deficits concerning schizophrenics is well-known. Much less material of that kind has been collected from patients with affective disorders, which was the aim of this clinical study.
Methods:
Inclusion criterions were in- and outpatients with affective disorders (ICD-10: F31-F33) aged < 61. The clinical status was determined by use of the HAMD-21, the subjects were examined by means of standardised computerised cognitive performance tests (CGT-[M], DAUF). The results were correlated with the HAMD and the psychiatric pharmacotherapy.
Results:
In each of the three subtests the heavily depressive group (HAMD > 24, n = 14) came off significantly (Mann-Whitney-U-Test, p < 0.05) worse than the remitted group (HAMD < or = 8, n = 18) while 8 of the 18 remitted patients showed pathological results in the CGT-(M). Only patients who took tranquilizers performed significantly worse than patients without such medication (p < 0.05).
Conclusion:
In some cases of affective disorders, a "cognitive residual syndrome" persists which is rather part of the disease than pharmacotherapy-associated.
More Related Videos
04:33Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
09:14Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Related Concept Videos
Depression: Overview
Cognitive Development During Adulthood
Depressive Disorders: MDD and Dysthymia
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Cognitive Therapy
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...