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Reactivity of 3-iodoimidazo[1,2-a]pyridines using a Suzuki-type cross-coupling reaction
C Enguehard1, J L Renou, V Collot
1Laboratoire de Chimie Thérapeutique, UFR des Sciences Pharmaceutiques, Tours, France.
The Journal of Organic Chemistry
|October 29, 2000
Abstract:
The influence of base and solvent in Suzuki cross-coupling reaction on various 2-substituted-3-iodoimidazo[1,2-a]pyridines was reported. The reactivity was largely influenced by nature of the substituent. Optimized yields and shortened times of reaction were obtained using strong bases in DME.