Desformylgramicidin: a model channel with an extremely high water permeability

S M Saparov1, Y N Antonenko, R E Koeppe

  • 1Martin-Luther-Universität, Medizinische Fakultät, Institut für Medizinische Physik und Biophysik, 06097 Halle, Germany.

Biophysical Journal
|October 29, 2000
PubMed

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Ion Channels

The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow specific...