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Solution- and solid-phase synthesis of peptide-substituted thiazolidinediones as potential PPAR ligands
D L Mohler1, G Shen, A K Dotse
1Department of Chemistry, Emory University, Atlanta, GA 30322, USA. dmohler@emory.edu
Bioorganic & Medicinal Chemistry Letters
|October 31, 2000
Abstract:
Solution- and solid-phase methods for the preparation of peptide-substituted thiazolidinediones have been developed as an approach towards the preparation of a library of these compounds as potential ligands for the peroxisome proliferator-activated receptors (PPARs).