Risk factors for sternal wound and other infections in pediatric cardiac surgery patients
P A Mehta1, C K Cunningham, C B Colella
1Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, USA.
Insights
Pediatric cardiac surgery patients face significant infection risks. Identifying risk factors like lower age and longer hospital stays can improve prevention and treatment strategies for sternal wound infections.
Area of Science:
- Pediatric cardiac surgery
- Infectious disease epidemiology
- Surgical site infections
Background:
- Infections pose a significant threat to pediatric cardiac surgery patients.
- Understanding infection incidence, pathogens, and risk factors is crucial.
Purpose of the Study:
- To determine the incidence, pathogens, and risk factors for sternal wound and other infections in children undergoing cardiac surgery.
Main Methods:
- Retrospective chart review of pediatric cardiac surgeries (1996-1998).
- Analysis focused on patients undergoing sternotomy to identify risk factors for sternal wound infection.
- Comparison of infected vs. non-infected patients for preoperative, intraoperative, and postoperative factors.
Main Results:
- Sternal wound infection occurred in 5% of pediatric cardiac surgery patients (10/202).
- Risk factors included younger age, higher American Society of Anesthesiologist score, longer preoperative stay, ventilation, inotropic support, and hospital stays.
- Staphylococcus aureus was the most common pathogen; other infections included pneumonia, UTI, and bacteremia.
Conclusions:
- Infections remain a major cause of morbidity in pediatric cardiac surgery.
- Identifying specific risk factors aids in developing targeted preventive and treatment strategies for high-risk children.
Background:
This study was undertaken to determine the incidence, pathogens and risk factors associated with development of sternal wound and other infections in children undergoing cardiac surgery.
Methods:
Retrospective chart review was performed for all cardiac surgeries performed on children <18 years of age at Upstate Medical University at Syracuse between January, 1996, and June, 1998. For evaluation of risk factors for sternal wound infection, only patients undergoing sternotomy are included in the analysis: those with infection are compared with those without for preoperative, intraoperative and postoperative risk factors.
Results:
Sternal wound infection developed in 10 of 202 (5%) children after median sternotomy. Superficial sternal wound infection developed in 6 (3%) children, and 4 (2%) had deep infection. Children with sternal wound infection had lower age, higher American Society of Anesthesiologist score, longer preoperative stay, longer period of ventilation and inotropic support, longer intensive care unit and total postoperative hospital stays and increased leukocyte band cell counts preoperatively and on Postoperative Day 1 than those without sternal infection. Causative agents for sternal wound infection were Staphylococcus aureus (6), Pseudomonas aeruginosa (1) and Haemophilus influenzae non-type b (1). In addition 32 bacterial infections occurred at nonsurgical sites after 28 procedures. Infections included pneumonia, urinary tract infection and bacteremia. Longer bypass time and longer operation time were two additional risk factors for nonwound infection.
Conclusion:
Infections continue to be a significant cause of morbidity in cardiac surgery patients. Knowledge of risk factors for infection could be useful in preventive and treatment strategies for these high-risk groups.
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