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[Assessment of the left ventricular function by tissue Doppler echocardiography]
M Olszowska1, M Hlawaty, M Kostkiewicz
1Klinika Chorób Serca i Naczyń, Instytutu Kardiologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
Insights
Myocardial velocity gradient, a new measure of left ventricular contraction, is significantly reduced in patients with myocardial infarction or dilated cardiomyopathy compared to healthy individuals.
Area of Science:
- Cardiology
- Medical Imaging
Context:
- Regional left ventricular contraction is crucial for cardiac function.
- Two-dimensional tissue Doppler imaging (TDI) offers advanced methods for assessing myocardial mechanics.
Purpose:
- To compare the myocardial velocity gradient (MVG) in patients with old myocardial infarction (MI) and dilated cardiomyopathy (DCM) against healthy controls.
- To evaluate MVG as a quantitative indicator of regional left ventricular contraction in these patient groups.
Summary:
- The study assessed MVG in 44 subjects (32 patients with MI or DCM, 12 healthy controls).
- Patients with old anteroseptal or posterior MI showed significantly lower MVG in infarct regions compared to non-infarct regions and controls.
- Patients with DCM exhibited significantly reduced MVG in both anteroseptal and posterior segments compared to healthy subjects.
Impact:
- Myocardial velocity gradient serves as a novel, quantitative biomarker for assessing regional left ventricular systolic function.
- This technique can aid in the diagnosis and management of conditions affecting myocardial contractility, such as MI and DCM.
Unlabelled:
Myocardial velocity gradient is a new indicator of regional left ventricular contraction determined by a two dimensional tissue Doppler imaging technique. The main goal of this study was to compare myocardial velocity gradient in patients with old myocardial infarction and dilated cardiomyopathy to normal subjects. We assessed myocardial velocity gradient in 44 persons: 32 patients (19 men, 13 women, mean aged 51.2 +/- 6.1 years) and 12 healthy subjects (7 men, 5 women, mean age 49.3 +/- 8.3 years) who were divided into 4 groups. Group A--14 patients with old anteroseptal myocardial infarction, group B--7 patients with old posterior infarction, group C--11 patients with dilated cardiomyopathy and group D--12 healthy subjects. In normal subjects myocardial velocity gradient in the anteroseptal segment was mean 2.44 +/- 0.34 s-1 and in the posterior segment was 3.08 +/- 0.38 s-1. Myocardial velocity gradient in the infarct regions was significantly lower than in noninfarct regions as well as that in the corresponding regions in normal subjects. Gradient in the anteroseptal and posterior segments was in group A: 0.61 +/- 0.33 s-1 12.39 +/- 0.65 s-1, p < 0.001 respectively and group B: 2.11 +/- 0.45 s-1 10.91 +/- 0.34 s-1, p < 0.001 respectively. In patients with dilated cardiomyopathy gradient was significantly lower (nteroseptal segment 0.55 +/- 0.37 s-1, posterior segment 0.85 +/- 0.31 s-1) than that in normal subjects (p < 0.001).
Conclusion:
Myocardial velocity gradient is a new indicator for the quantitative assessment of regional left ventricular contraction.