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Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
08:15

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules

Published on: October 17, 2014

The armadillo repeat region targets ARVCF to cadherin-based cellular junctions.

U Kaufmann1, C Zuppinger, Z Waibler

  • 1Institut der Anthropologie und Humangenetik fuer Biologen, Johann-Wolfgang-Goethe-Universitaet Frankfurt, Siesmayerstrasse 70, D-60054 Frankfurt/Main, Germany.

Journal of Cell Science
|November 1, 2000
PubMed
Summary

ARVCF, a p120 subfamily member, binds to M-cadherin, linking the cytoskeleton to cell membranes. Its armadillo repeats are crucial for this interaction, essential for junctional localization.

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