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Persistent cough: differential diagnosis
J A Bellanti1, S O Tutuncuoglu, M Azem
1Department of Pediatrics, Georgetown University Medical Center, Washington, D.C., USA.
Persistent cough, a common respiratory issue, warrants a thorough differential diagnosis. Understanding airway innervation and cough mechanisms is key to patient management.
Area of Science:
- Pulmonology
- Respiratory Medicine
- Physiology
Background:
- Cough is a common symptom, leading to millions of medical visits annually.
- Persistent cough, lasting over three weeks, significantly impacts patient care.
- Understanding the underlying mechanisms is crucial for effective diagnosis and treatment.
Purpose of the Study:
- To explore the differential diagnosis of persistent cough.
- To detail the autonomic innervation of human airways.
- To elucidate the mechanisms of cough and outline a patient approach.
Main Methods:
- Review of current literature on cough physiology and diagnosis.
- Examination of autonomic nervous system's role in airway function.
- Analysis of diagnostic strategies for persistent cough.
Main Results:
- Persistent cough necessitates a systematic diagnostic approach.
- Autonomic innervation plays a significant role in airway reflexes.
- Multiple factors contribute to the complex mechanisms of cough.
Conclusions:
- A comprehensive understanding of cough mechanisms and airway innervation is essential.
- Effective management of persistent cough relies on accurate differential diagnosis.
- This review provides a framework for approaching patients with persistent cough.
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