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Related Concept Videos

Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

3.9K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
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Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

8.0K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

2.1K
Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
2.1K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

3.3K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.3K
Bone Disorders01:29

Bone Disorders

5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

3.6K
As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
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Related Experiment Video

Updated: Jan 3, 2026

Co-localization of Cell Lineage Markers and the Tomato Signal
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Co-localization of Cell Lineage Markers and the Tomato Signal

Published on: December 28, 2016

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Benign chondroid neoplasms of bone.

M R Robbin1, M D Murphey

  • 1Department of Radiology, University Hospitals of Cleveland, Case Western University School of Medicine, Ohio, USA.

Seminars in Musculoskeletal Radiology
|November 4, 2000
PubMed
Summary

This article details common benign cartilage tumors like osteochondroma and chondroblastoma. It highlights characteristic "ring and arc" mineralization seen on imaging for accurate diagnosis.

Area of Science:

  • Orthopedic Radiology
  • Skeletal Radiology
  • Pediatric Radiology

Background:

  • Benign cartilage lesions are common bone tumors.
  • Accurate diagnosis is crucial for appropriate management.
  • Imaging plays a key role in identifying these lesions.

Purpose of the Study:

  • To review the imaging spectrum of common benign cartilage lesions.
  • To emphasize the characteristic imaging findings, including "ring and arc" mineralization.
  • To promote a multimodality imaging approach for diagnosis.

Main Methods:

  • Review of imaging findings for various benign cartilage tumors.
  • Correlation of imaging features with histopathology.
  • Emphasis on characteristic mineralization patterns.

More Related Videos

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
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Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification

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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

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Related Experiment Videos

Last Updated: Jan 3, 2026

Co-localization of Cell Lineage Markers and the Tomato Signal
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Co-localization of Cell Lineage Markers and the Tomato Signal

Published on: December 28, 2016

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Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
07:23

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification

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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

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Main Results:

  • Osteochondroma, chondroblastoma, periosteal chondroma, and chondromyxoid fibroma are discussed.
  • "Ring and arc" mineralization is a key feature of cartilage lesions.
  • Multimodality imaging aids in differentiating these lesions.

Conclusions:

  • Benign cartilage tumors have distinct imaging appearances.
  • Characteristic mineralization is indicative of cartilage origin.
  • A multimodality approach optimizes diagnostic accuracy for these lesions.