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Subvalvular left ventricular aneurysms

J Deshpande1, P Vaideeswar, A Sivaraman

  • 1Department of Pathology, Topiwala National Medical College, Mumbai-400008, India. atharnas@yahoo.com

Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology
|November 7, 2000
PubMed

Insights

This study reviewed 19 subvalvular left ventricular aneurysms, finding distinct associations: subaortic aneurysms with infective endocarditis and submitral aneurysms with tuberculosis, suggesting varied etiologies.

Area of Science:

  • Cardiovascular Pathology
  • Cardiac Surgery

Background:

  • Subvalvular left ventricular aneurysms (SVLVA) are rare cardiac conditions.
  • They can occur as subaortic or submitral types with diverse causes.

Purpose of the Study:

  • To retrospectively analyze the clinical characteristics and etiological associations of subvalvular aneurysms.
  • To investigate potential links between aneurysm location and underlying conditions.

Main Methods:

  • Retrospective review of 16 cases with 19 subvalvular aneurysms.
  • Classification of aneurysms into subaortic, submitral, or mixed types.
  • Analysis of patient history and associated pathologies.

Main Results:

  • 12 isolated subaortic aneurysms, 3 isolated submitral aneurysms, and 1 case with multiple types were identified.
  • Subaortic aneurysms showed association with infective endocarditis.
  • Submitral aneurysms demonstrated a strong association with tuberculosis.
  • Five cases had associated sinus of Valsalva aneurysms, suggesting congenital weakness.

Conclusions:

  • Subvalvular left ventricular aneurysms have varied etiologies.
  • Infective endocarditis is linked to subaortic types, while tuberculosis is associated with submitral types.
  • Congenital factors may contribute to the development of these aneurysms, particularly when associated with sinus of Valsalva aneurysms.

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