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This study analyzed 639 patients with acute esophagogastroduodenal bleeding, finding ulcer disease as the primary cause. Treatment outcomes revealed complications in 24.9% and a mortality rate of 8.6%.
Area of Science:
- Gastroenterology
- Internal Medicine
- Clinical Research
Background:
- Acute esophagogastroduodenal bleeding is a significant clinical challenge.
- Understanding the etiology and treatment outcomes is crucial for patient management.
Purpose of the Study:
- To analyze the causes and treatment outcomes of acute esophagogastroduodenal bleeding in a large patient cohort.
- To evaluate the effectiveness of conservative and surgical interventions.
Main Methods:
- Retrospective analysis of 639 patients diagnosed with acute esophagogastroduodenal bleeding.
- Categorization of bleeding causes including ulcer disease, gastric tumors, erosive gastritis, and portal hypertension.
- Assessment of treatment modalities (conservative vs. surgical) and associated complications.
Main Results:
- Ulcer disease was the most frequent cause (66.4%).
- Conservative treatment was administered to 59% of patients, while 41% underwent surgery.
- Complications occurred in 24.9% of patients, with an 8.6% mortality rate.
Conclusions:
- Peptic ulcer disease remains the leading cause of acute upper gastrointestinal bleeding.
- A significant proportion of patients experience complications, highlighting the severity of this condition.
- Further research into optimizing treatment strategies is warranted to reduce morbidity and mortality.
Abstract:
The results of treatment of 639 patients with acute esophagogastroduodenal bleeding have been analysed. There were the following causes of bleeding: in 66.4%--ulcer disease, in 9.1%--gastric tumours, in 7.3%--erosive gastritis, in 6.4%--portal hypertension, in 9.1%--the other. In 1.7% of patients, a cause was not established. Conservative treatment was performed in 59% of patients, surgery--in 41%. Complications developed in 24.9% of the patients, 8.6% died.